CAV3 Polyclonal Antibody

CAV3, CAV3, Caveolin 3, Caveolin-3, LGMD1C, LQT9, M-caveolin, MGC126100, MGC126101, MGC126129, OTTHUMP00000115603, OTTHUMP00000207105, VIP 21, VIP21

This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

WB 1:500-1:2000, IHC 1:50-1:200

17kDa

sc-7665, sc-5437, sc-30753, sc-30752, sc-55518, sc-28828