Item no. |
E-AB-16187-120 |
Manufacturer |
Elabscience
|
Amount |
120uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
CSDD 2, CSDD2, FLJ16517, Lin 28 homolog B (C. elegans), Lin 28.2, Lin-28B, LIN28B, LN28B, Protein lin-28 homolog B |
Similar products |
LIN28B, CSDD2, Protein lin-28 homolog B, Lin-28B, FLJ16517, LN28B, CSDD 2, Lin 28.2, Lin 28 homolog B (C. elegans) |
Available |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling |
Synonyms |
CSDD 2, CSDD2, FLJ16517, Lin 28 homolog B (C. elegans), Lin 28.2, Lin-28B, LIN28B, LN28B, Protein lin-28 homolog B |
Swissprot |
Q6ZN17 |
Background |
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012] |
Concentration |
0.3 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthetic peptide of human LIN28B |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:500-1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
27kDa |
Gene Accession |
NP_001004317 |
Santa Cruz # |
sc-130802 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.