Item no. |
E-AB-13312-20 |
Manufacturer |
Elabscience
|
Amount |
20uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
17 beta HSD 1, 17 beta hydroxysteroid dehydrogenase type 1, 17-beta-HSD 1, 17-beta-hydroxysteroid dehydrogenase type 1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, DHB1, E17KSR, E2DH, EDH17B1, EDH17B2, EDHB17, Estradiol 17 beta dehydrogenase 1, E |
Similar products |
HSD17B1, E17KSR, EDH17B1, EDH17B2, EDHB17, Estradiol 17-beta-dehydrogenase 1, 17-beta-hydroxysteroid dehydrogenase type 1, 20 alpha-hydroxysteroid dehydrogenase, E2DH, Placental 17-beta-hydroxysteroid dehydrogenase, member 1, HSD17, SDR28C1, DHB1, 17 beta HSD 1, 17 beta hydroxysteroid dehydrogenase type 1, 17-beta-HSD 1, 20-alpha-HSD, Estradiol 17 beta dehydrogenase 1, Placental 17 beta hydroxysteroid dehydrogenase, Short chain dehydrogenase/reductase family 28CE, Hydroxysteroid (17 beta) dehydrogenase 1, MGC13814 |
Available |
|
Research Areas |
Cancer, Metabolism, Neuroscience, Signal Transduction |
Synonyms |
17 beta HSD 1, 17 beta hydroxysteroid dehydrogenase type 1, 17-beta-HSD 1, 17-beta-hydroxysteroid dehydrogenase type 1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, DHB1, E17KSR, E2DH, EDH17B1, EDH17B2, EDHB17, Estradiol 17 beta dehydrogenase 1, Estradiol 17-beta-dehydrogenase 1, HSD17, HSD17B1, Hydroxysteroid (17 beta) dehydrogenase 1, MGC13814, Placental 17 beta hydroxysteroid dehydrogenase, Placental 17-beta-hydroxysteroid dehydrogenase, SDR28C1, Short chain dehydrogenase/reductase family 28CE, member 1 |
Swissprot |
P14061 |
Background |
Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy. |
Concentration |
0.9 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthetic peptide of human HSD17B1 |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:500-1:2000, IHC 1:50-1:200 |
Conjugation |
Unconjugated |
Calculated MW |
35kDa |
Gene Accession |
NP_000404 |
Santa Cruz # |
sc-26964, sc-26963, sc-26965, sc-32872, sc-32871 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.