Item no. |
E-AB-10826-120 |
Manufacturer |
Elabscience
|
Amount |
120uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
activity regulated cytoskeleton associated protein, activity regulated gene 3.1 protein homolog, Activity-regulated cytoskeleton-associated protein, Activity-regulated gene 3.1 protein homolog, Arc, ARC/ARG3.1, ARC, Arg3.1 |
Similar products |
ARC, Arc, Arg3.1, Activity-regulated cytoskeleton-associated protein, ARC/ARG3.1, Activity-regulated gene 3.1 protein homolog, activity regulated cytoskeleton associated protein, activity regulated gene 3.1 protein homolog |
Available |
|
Research Areas |
Cancer, Neuroscience |
Synonyms |
activity regulated cytoskeleton associated protein, activity regulated gene 3.1 protein homolog, Activity-regulated cytoskeleton-associated protein, Activity-regulated gene 3.1 protein homolog, Arc, ARC/ARG3.1, ARC, Arg3.1 |
Swissprot |
Q7LC44 |
Background |
Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum. |
Concentration |
0.5 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human ARC |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
IHC 1:50-1:200 |
Conjugation |
Unconjugated |
Gene Accession |
BC012321 |
Santa Cruz # |
sc-33947, sc-6381, sc-6382, sc-15325 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.