Item no. |
CSB-YP326510RA-1 |
Manufacturer |
Cusabio
|
Amount |
1mg |
Quantity options |
1mg
10ug
100ug
20ug
200ug
50ug
500ug
|
Category |
|
Type |
Proteins Recombinant |
Format |
Liquid or Lyophilized powder |
Specific against |
other |
Purity |
Greater than 85% as determined by SDS-PAGE. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Available |
|
Research Topic |
Others |
Uniprot ID |
P25031 |
Gene Names |
Reg3b |
Organism |
Rattus norvegicus (Rat) |
AA Sequence |
EDSPKKIPSARISCPKGSQAYGSYCYALFQIPQTW FDAELACQKRPEGHLVSVLNVAEASFLASMVKNTG NSYQYTWIGLHDPTLGGEPNGGGWEWSNNDIMNYV NWERNPSTALDRGFCGSLSRSSGFLRWRDTTCEVK LPYVCKFTG |
Expression Region |
27-175aa |
Sequence Info |
Full Length of Mature Protein |
Source |
Yeast |
Tag Info |
N-terminal 6xHis-sumostar-tagged |
MW |
32.6 kDa |
Alternative Name(s) |
Pancreatitis-associated protein 1; Peptide 23REG-2Regenerating islet-derived protein III-beta ; Reg III-beta |
Relevance |
Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues . |
Reference |
Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectin-related protein overexpressed during acute experimental pancreatitis.Iovanna J., Orelle B., Keim V., Dagorn J.-C.J. Biol. Chem. 266:24664-24669(1991) |
Purity |
Greater than 85% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues (By similarity). |
Involvement in disease |
Overexpressed during the acute phase of pancreatitis. |
Subcellular Location |
Secreted |
Tissue Specificity |
Constitutively expressed in intestine. |
Tag Information |
N-terminal 6xHis-sumostar-tagged |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.