Item no. |
CSB-YP011095MO-1 |
Manufacturer |
Cusabio
|
Amount |
1mg |
Category |
|
Type |
Proteins Recombinant |
Format |
Liquid or Lyophilized powder |
Specific against |
other |
Host |
Yeast |
Purity |
Greater than 90% as determined by SDS-PAGE. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Available |
|
Research Topic |
Others |
Uniprot ID |
P47876 |
Gene Names |
Igfbp1 |
Organism |
Mus musculus (Mouse) |
AA Sequence |
APQPWHCAPCTAERLGLCPPVPASCPEISRPAGCG CCPTCALPMGAACGVATARCAQGLSCRALPGEPRP LHALTRGQGACVPEPAAPATSTLFSSQHEEAKAAV VSADELSESPEMTEEQLLDSFHLMAPSREDQPILW NAISTYSSMRAREIADLKKWKEPCQRELYKVLERL AAAQQKAGDEIYKFYLPNCNKNGFYHSKQCETSLD GEAGLCWCVYPWSGKKIPGSLETRGDPNCHQYFNV HN |
Expression Region |
26-272aa |
Sequence Info |
Full Length of Mature Protein |
Source |
Yeast |
Tag Info |
N-terminal 6xHis-tagged |
MW |
28.9 kDa |
Relevance |
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration . |
Reference |
cDNA cloning and mRNA expression of the six mouse insulin-like growth factor binding proteins.Schuller A.G.P., Groffen C., van Neck J.W., Zwarthoff E.C., Drop S.L.S.Mol. Cell. Endocrinol. 104:57-66(1994) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration (By similarity). |
Subcellular Location |
Secreted |
Tag Information |
N-terminal 6xHis-tagged |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.