Item no. |
CSB-YP004856HU-1 |
Manufacturer |
Cusabio
|
Amount |
1mg |
Category |
|
Type |
Proteins Recombinant |
Format |
Liquid or Lyophilized powder |
Specific against |
other |
Host |
Yeast |
Purity |
Greater than 90% as determined by SDS-PAGE. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
CCT-beta |
Available |
|
Research Topic |
Signal Transduction |
Uniprot ID |
P78371 |
Gene Names |
CCT2 |
Organism |
Homo sapiens (Human) |
AA Sequence |
ASLSLAPVNIFKAGADEERAETARLTSFIGAIAIG DLVKSTLGPKGMDKILLSSGRDASLMVTNDGATIL KNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLA AELLREAESLIAKKIHPQTIIAGWREATKAAREAL LSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHK DHFTKLAVEAVLRLKGSGNLEAIHIIKKLGGSLAD SYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDT DKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVER ILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHAD FAGVERLALVTGGEIASTFDHPELVKLGSCKLIEE VMIGEDKLIHFSGVALGEACTIVLRGATQQILDEA ERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAV TQLANRTPGKEAVAMESYAKALRMLPTIIADNAGY DSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAIL GITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPR KRVPDHHPC |
Expression Region |
2-535aa |
Sequence Info |
Full Length of Mature Protein |
Source |
Yeast |
Tag Info |
N-terminal 6xHis-tagged |
MW |
59.4 kDa |
Alternative Name(s) |
CCT-beta |
Relevance |
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. |
Reference |
"Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT."Won K.-A., Schumacher R.J., Farr G.W., Horwich A.L., Reed S.I.Mol. Cell. Biol. 18:7584-7589(1998) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. |
Subcellular Location |
Cytoplasm |
Protein Families |
TCP-1 chaperonin family |
Tag Information |
N-terminal 6xHis-tagged |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.