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Recombinant Human C4b-binding protein alpha chain(C4BPA)

Recombinant Human C4b-binding protein alpha chain(C4BPA)

Item no.	CSB-YP003951HU-200
Manufacturer	Cusabio
Amount	200ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Host	Yeast
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Proline-rich protein,Short name:,PRP
Available
Alternative Name(s)	Proline-rich protein Short name: PRP
AA Sequence	NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLP GYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGE LRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSR CEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSG EENFYAYGFSVTYSCDPRFSLLGHASISCTVENET IGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYN YKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPA CEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVL RYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEAL CCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFS CHETSRFSAICQGDGTWSPRTPSCGDICNFPPKIA HGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSC SYSHWSAPAPQCKALCRKPELVNGRLSVDKDQYVE PENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKC EWETPEGCEQVLTGKRLMQCLPNPEDVKMALEVYK LSLEIEQLELQRDSARQSTLDKEL
Research Topic	Immunology
Uniprot ID	P04003
Gene Names	C4BPA
Tag Info	N-terminal 6xHis-tagged
Expression Region	49-597aa
MW of Fusion Proten	63, 7
Sequence Info	Full Length
Relevance	Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
Reference	"Molecular cloning and characterization of the cDNA coding for C4b-binding protein, a regulatory protein of the classical pathway of the human complement system."Chung L.P., Bentley D.R., Reid K.B.M.Biochem. J. 230:133-141(1985)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	Tris-based buffer, 50% glycerol
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Species	Homo sapiens (Human)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200ug

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