Item no. |
CSB-EP818263HUa0-200 |
Manufacturer |
Cusabio
|
Amount |
200ug |
Quantity options |
1mg
10ug
100ug
20ug
200ug
50ug
500ug
|
Category |
|
Type |
Proteins Recombinant |
Format |
Liquid or Lyophilized powder |
Specific against |
other |
Purity |
Greater than 85% as determined by SDS-PAGE. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Available |
|
Research areas |
Others |
Target / Protein |
TMEFF1 |
Biologically active |
Not Test |
Expression system |
E.coli |
Species of origin |
Homo sapiens (Human) |
Uniprot ID |
Q8IYR6 |
AA Sequence |
SNQPPGGGGGSGGDCPGGKGKSINCSELNVRESDV RVCDESSCKYGGVCKEDGDGLKCACQFQCHTNYIP VCGSNGDTYQNECFLRRAACKHQKEITVIARGPCY SDNGSGSGEGEEEGSGAEVHRKHSKCGPCKYKAEC DEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPC FVREASCIKQEQIDIRHLGHCTDTDDTSLLGKKDD GLQYRPDVKDASDQREDVYIGNHMPCPENLNGYCI HGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILY VVPSRQKLTHV |
Tag Info |
N-terminal 6xHis-tagged |
Expression Region |
40-330aa |
Protein length |
Partial |
MW |
35.5 kDa |
Alternative Name(s) |
H7365 Transmembrane protein with EGF-like and one follistatin-like domain C9orf2 |
Relevance |
May inhibit NODAL and BMP signaling during neural patterning. May be a tumor suppressor in brain cancers. |
References |
"A novel transmembrane protein with epidermal growth factor and follistatin domains expressed in the hypothalamo-hypophysial axis of Xenopus laevis." Eib D.W., Martens G.J.M. J. Neurochem. 67:1047-1055(1996) |
Purity |
Greater than 85% as determined by SDS-PAGE. |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers. |
Subcellular Location |
Cell membrane, Single-pass type I membrane protein |
Protein Families |
Tomoregulin family |
Tissue Specificity |
Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues. |
Tag Information |
N-terminal 6xHis-tagged |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.