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Recombinant Dog Interleukin-8(IL8)

Recombinant Dog Interleukin-8(IL8)

Item no.	CSB-EP011671DO-500
Manufacturer	Cusabio
Amount	500ug
Quantity options	1mg 10ug 100ug 20ug 200ug 50ug 500ug
Category	Neuroscience Neuroinflammation Metabolism Diabetes Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid or Lyophilized powder
Specific against	other
Host	E.coli
Conjugate/Tag	GST
Purity	Greater than 90% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	C-X-C motif chemokine hemokine (C-X-C motif) ligand 8
Available
Research Topic	Others
Uniprot ID	P41324
Gene Names	IL8
Organism	Canis lupus familiaris (Dog) (Canis familiaris)
AA Sequence	AVLSRVSSELRCQCIKTHSTPFHPKYIKELRVIDS GPHCENSEIIVKLFNGNEVCLDPKEKWVQKVVQIF LKKAEKQDP
Expression Region	23-101aa
Sequence Info	Full Length of Mature Protein
Source	E.coli
Tag Info	N-terminal GST-tagged
MW	36.1 kDa
Alternative Name(s)	C-X-C motif chemokine hemokine (C-X-C motif) ligand 8
Relevance	IL-8 is a chotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus.
Reference	Borrelia burgdorferi migrates into joint capsules and causes an up-regulation of interleukin-8 in synovial membranes of dogs experimentally infected with ticks.Straubinger R.K., Straubinger A.F., Harter L., Jacobson R.H., Chang Y.-F., Summers B.A., Erb H.N., Appel M.J.Infect. Immun. 65:1273-1285(1997)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	Tris-based buffer, 50% glycerol
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus.
Subcellular Location	Secreted
Protein Families	Intercrine alpha (chemokine CxC) family
Tag Information	N-terminal GST-tagged

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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