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Recombinant Rat Dipeptidyl aminopeptidase-like protein 6(Dpp6),partial

Recombinant Rat Dipeptidyl aminopeptidase-like protein 6(Dpp6),partial

Item no.	CSB-EP007140RA-50
Manufacturer	Cusabio
Amount	50ug
Quantity options	1mg 10ug 100ug 20ug 200ug 50ug 500ug
Category	Neuroscience Targets for Rodent Neurosciences Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid or Lyophilized powder
Specific against	other
Host	E.coli
Purity	Greater than 90% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DPPXDipeptidyl aminopeptidase-related proteinDipeptidyl peptidase 6Dipeptidyl peptidase IV-like proteinDipeptidyl peptidase VI ;DPP VI
Available
Research Topic	Others
Uniprot ID	P46101
Gene Names	DPP6
Organism	Rattus norvegicus (Rat)
AA Sequence	LTPAEDTSLSQKKKVTVEDLFSEDFKIHDPEAKWI SDKEFIYRERKGSVILRNVETNNSTVLIEGKKIES LRAIRYEISPDKEYALFSYNVEPVYQHSHTGYYVL SKIPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIF IFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDW LYEEEILKSHIAHWWSPDGTRLAYATINDSRVPLM ELPTYTGSVYPTVKPYHYPKAGSENPSISLHVIGL NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAV TWLNRAQNVSILTLCDATTGVCTKKHEDESEAWLH RQNEEPVFSKDGRKFFFVRAIPQGGRGKFYHITVS SSQPNSSNDNIQSITSGDWDVTEILTYDEKRNKLY FLSTEDLPRRRHLYSANTVDDFNRQCLSCDLVENC TYVSASFSHNMDFFLLKCEGPGVPTVTVHNTTDKR RMFDLEANEQVQKAIYDRQMPKIEYRKIEVEDYSL PMQILKPATFTDTAHYPLLLVVDGTPGSQSVSERF EVTWETVLVSSHGAVVVKCDGRGSGFQGTKLLHEV RRRLGFLEEKDQMEAVRTMLKEQYIDKTRVAVFGK DYGGYLSTYILPAKGENQGQTFTCGSALSPITDFK LYASAFSERYLGLHGLDNRAYEMTKLAHRVSALED QQFLIIHATADEKIHFQHTAELITQLIKGKANYSL QIYPDESHYFHSVALKQHLYRSIIGFFVECFRIQD KLPTATAKEDEEED
Expression Region	111-859aa
Sequence Info	Extracellular Domain
Source	E.coli
Tag Info	N-terminal 6xHis-tagged
MW	89.6 kDa
Alternative Name(s)	DPPXDipeptidyl aminopeptidase-related proteinDipeptidyl peptidase 6Dipeptidyl peptidase IV-like proteinDipeptidyl peptidase VI ; DPP VI
Relevance	Promotes cell surface expression of the potassium channel KCND2 . Modulates the activity and gating characteristics of the potassium channel KCND2 . Has no dipeptidyl aminopeptidase activity .
Reference	The dipeptidyl-peptidase-like protein DPP6 determines the unitary conductance of neuronal Kv4.2 channels.Kaulin Y.A., De Santiago-Castillo J.A., Rocha C.A., Nadal M.S., Rudy B., Covarrubias M.J. Neurosci. 29:3242-3251(2009)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	Tris-based buffer, 50% glycerol
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Promotes cell surface expression of the potassium channel KCND2
Subcellular Location	Cell membrane, Single-pass type II membrane protein
Protein Families	Peptidase S9B family
Tissue Specificity	Detected in brain cortex, hippocampus, thalamus and cerebellum granule cells (at protein level) (PubMed:16123112). Isoform DPPX-S is expressed in brain and some peripheral tissues including kidney, ovary, and testis; in contrast isoform DPPX-L is expressed almost exclusively in brain.
Tag Information	N-terminal 6xHis-tagged

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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