Comparison

Recombinant Human Protein Wnt-2b(WNT2B)

Item no. CSB-CF856613HU-10
Manufacturer Cusabio
Amount 10ug
Category
Type Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Purity Greater than 90% as determined by SDS-PAGE.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Protein Wnt-13
Available
Research Topic
Stem Cells
Uniprot ID
Q93097
Gene Names
WNT2B
Organism
Homo sapiens(Human)
AA Sequence
MLRPGGAEEAAQLPLRRASAPVPVPSPAAPDGSRA SARLGLACLLLLLLLTLPARVDTSWWYIGALGARV ICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIR ECQHQFRHHRWNCTTLDRDHTVFGRVMLRSSREAA FVYAISSAGVVHAITRACSQGELSVCSCDPYTRGR HHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRL KDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGS CTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQD GANFTAARQGYRRATRTDLVYFDNSPDYCVLDKAA GSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVT RVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKA EWLDQT
Expression Region
1-391aa
Sequence Info
Full Length
Source
in vitro E.coli expression system
Tag Info
N-terminal 6xHis-SUMO-tagged
MW
59.8 kDa
Alternative Name(s)
Protein Wnt-13
Relevance
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis.
Reference
"Complete sequencing and characterization of 21, 243 full-length human cDNAs."Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage Buffer
Tris-based buffer, 50% glycerol
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis.
Subcellular Location
Secreted, extracellular space, extracellular matrix
Protein Families
Wnt family
Tissue Specificity
Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines.
Paythway
Hipposignalingpathway
Tag Information
N-terminal 6xHis-SUMO-tagged

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10ug
Available: In stock
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