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Recombinant Human Ciliary neurotrophic factor protein(CNTF) (Active)

Recombinant Human Ciliary neurotrophic factor protein(CNTF) (Active)

Item no.	CSB-AP002841HU-20
Manufacturer	Cusabio
Amount	20ug
Quantity options	1mg 100ug 20ug 250ug 5ug 500ug
Category	Neuroscience Metabolism Diabetes Regulation of Appetite Molecular Targets for Neuroscience Neural Signaling Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized powder
Specific against	other
Host	E.coli
Purity	>97% as determined by SDS-PAGE and HPLC.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CNTF,
Available
Classification	Cytokine
Subdivision	Growth Factor
Research Areas	Neuroscience
Uniprot NO.	P26441
Uniprot Entry Name	CNTF_HUMAN
Gene Names	CNTF
Source	E.Coli
Expression Region	1-200aa
Sequence	MAFTEHSPLT PHRRDLCSRS IWLARKIRSD LT ALTESYVK HQGLNKNINL DSADGMPVAS TDQW SELTEA ERLQENLQAY RTFHVLLARL LEDQQV HFTP TEGDFHQAIH TLLLQVAAFA YQIEELMI LL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG S HYIANNKKM
Protein Description	Full Length
Tag Info	Tag-Free
Mol. Weight	22.9 kDa
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 150 ng/ml, corresponding to a specific activity of ? 6.7 x 103 IU/mg.
Purity	>97% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Alias	CNTF,
Relevance	CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
PubMed ID	1861138; 1915374; 1840538; 1883844; 8075647; 14702039; 15489334; 7796798; 10391209
Function	CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Subcellular Location	Cytoplasm
Protein Families	CNTF family
Tissue Specificity	Nervous system.
Paythway	Jak-STATsignalingpathway
Tag Information	Tag-Free

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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