Item no. |
CSB-AP002071HU-2 |
Manufacturer |
Cusabio
|
Amount |
2ug |
Category |
|
Type |
Proteins Recombinant |
Format |
Lyophilized powder |
Specific against |
other |
Host |
E.coli |
Purity |
>98% as determined by SDS-PAGE and HPLC. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
G-CSF, Filgrastim, Lenograstim |
Available |
|
Classification |
Cytokine |
Subdivision |
Colony Stimulating Factor |
Research Areas |
Immunology |
Uniprot NO. |
P09919 |
Uniprot Entry Name |
CSF3_HUMAN |
Gene Names |
CSF3, C17orf33, GCSF |
Source |
E.Coli |
Expression Region |
31-204aa |
Sequence |
TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQ EKLCATYK LCHPEELVLL GHSLGIPWAP LSSC PSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGIS PELG PTLDTLQLDV ADFATTIWQQ MEELGMAP AL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP |
Protein Description |
Partial of Isoform Short |
Tag Info |
Tag-Free |
Mol. Weight |
18.7 kDa |
Biological Activity |
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine NFS-60 cells is less than 0.1 ng/ml, corresponding to a specific activity of ? 1.0 x 107 IU/mg. |
Purity |
>98% as determined by SDS-PAGE and HPLC. |
Endotoxin |
Less than 1.0 EU/ug as determined by LAL method. |
Storage Buffer |
0.2 um filtered 10mM sodium acetate buffer, containing 5 % trehalose, pH 4.0 , lyophilized |
Alias |
G-CSF, Filgrastim, Lenograstim |
Relevance |
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. |
PubMed ID |
3484805; 2423327; 3494801; 15028279; 16625196; 2420009; 8554326; 7685769; 1281794; 7518249; 7685117; 10537111; 16492764 |
Function |
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. |
Subcellular Location |
Secreted |
Protein Families |
IL-6 superfamily |
Paythway |
Jak-STATsignalingpathway |
Tag Information |
Tag-Free |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.