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Recombinant Mouse C-X-C motif chemokine 11 protein(Cxcl11) (Active)

Recombinant Mouse C-X-C motif chemokine 11 protein(Cxcl11) (Active)

Item no.	CSB-AP001151MO-5
Manufacturer	Cusabio
Amount	5ug
Quantity options	1mg 100ug 20ug 250ug 5ug 500ug
Category	Neuroscience Neural Lineage Markers Peptides & Proteins Recombinant Proteins Stem Cell Markers
Type	Proteins Recombinant
Format	Lyophilized powder
Specific against	other
Host	E.coli
Purity	>98% as determined by SDS-PAGE and HPLC.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Interferon-inducible T-cell alpha chemoattractant, Small-inducible cytokine B11
Available
Classification	Cytokine
Subdivision	Chemokine
Research Areas	Immunology
Uniprot NO.	Q9JHH5
Uniprot Entry Name	CXL11_MOUSE
Gene Names	Cxcl11, Scyb11
Source	E.Coli
Expression Region	22-100aa
Sequence	FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YP SNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLI MQAIEK KNFLRRQNM
Protein Description	Full Length of Mature Protein
Tag Info	Tag-Free
Mol. Weight	9.1 kDa
Biological Activity	Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine CXCR3 transfected 293 cells is in a concentration of 10-100 ng/ml.
Purity	>98% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Alias	Interferon-inducible T-cell alpha chemoattractant, Small-inducible cytokine B11
Relevance	Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (By similarity). {ECO:0000250}.
PubMed ID	10828609; 10843686
Function	Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (By similarity).
Subcellular Location	Secreted
Protein Families	Intercrine alpha (chemokine CxC) family
Tag Information	Tag-Free

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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