Item no. |
CSB-AP001151MO-100 |
Manufacturer |
Cusabio
|
Amount |
100ug |
Quantity options |
1mg
100ug
20ug
250ug
5ug
500ug
|
Category |
|
Type |
Proteins Recombinant |
Format |
Lyophilized powder |
Specific against |
other |
Host |
E.coli |
Purity |
>98% as determined by SDS-PAGE and HPLC. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Interferon-inducible T-cell alpha chemoattractant, Small-inducible cytokine B11 |
Available |
|
Classification |
Cytokine |
Subdivision |
Chemokine |
Research Areas |
Immunology |
Uniprot NO. |
Q9JHH5 |
Uniprot Entry Name |
CXL11_MOUSE |
Gene Names |
Cxcl11, Scyb11 |
Source |
E.Coli |
Expression Region |
22-100aa |
Sequence |
FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YP SNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLI MQAIEK KNFLRRQNM |
Protein Description |
Full Length of Mature Protein |
Tag Info |
Tag-Free |
Mol. Weight |
9.1 kDa |
Biological Activity |
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine CXCR3 transfected 293 cells is in a concentration of 10-100 ng/ml. |
Purity |
>98% as determined by SDS-PAGE and HPLC. |
Endotoxin |
Less than 1.0 EU/ug as determined by LAL method. |
Storage Buffer |
0.2 um filtered PBS, pH 7.4 , lyophilized |
Alias |
Interferon-inducible T-cell alpha chemoattractant, Small-inducible cytokine B11 |
Relevance |
Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (By similarity). {ECO:0000250}. |
PubMed ID |
10828609; 10843686 |
Function |
Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (By similarity). |
Subcellular Location |
Secreted |
Protein Families |
Intercrine alpha (chemokine CxC) family |
Tag Information |
Tag-Free |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.