Manufacturer |
Cusabio
|
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Format |
Lyophilized powder |
Amount |
20ug |
Host |
E.coli |
Item no. |
CSB-AP000671HU-20 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Alias |
ENA-78, Epithelial-derived neutrophil-activating protein 78, Neutrophil-activating peptide ENA-78, Small-inducible cytokine B5, |
Purity |
>95% as determined by SDS-PAGE and HPLC. |
Classification |
Cytokine |
Subdivision |
Chemokine |
Research Areas |
Immunology |
Uniprot NO. |
P42830 |
Uniprot Entry Name |
CXCL5_HUMAN |
Gene Names |
CXCL5, ENA78, SCYB5 |
Source |
E.Coli |
Expression Region |
44-114aa |
Sequence |
LRELRCVCLQ TTQGVHPKMI SNLQVFAIGP QC SKVEVVAS LKNGKEICLD PEAPFLKKVI QKIL DGGNKE N |
Protein Description |
Partial |
Tag Info |
Tag-Free |
Mol. Weight |
7.8 kDa |
Biological Activity |
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration of 10.0-100.0 ng/ml. |
Purity |
>95% as determined by SDS-PAGE and HPLC. |
Endotoxin |
Less than 1.0 EU/ug as determined by LAL method. |
Storage Buffer |
0.2 um filtered PBS, pH 7.4 , lyophilized |
Alias |
ENA-78, Epithelial-derived neutrophil-activating protein 78, Neutrophil-activating peptide ENA-78, Small-inducible cytokine B5, |
Relevance |
Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. {ECO:0000269|PubMed:10095777}. |
PubMed ID |
7828901; 7929219; 7999089; 11468158; 15489334; 1744577; 10095777; 12665801; 14711052 |
Function |
Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. |
Subcellular Location |
Secreted |
Protein Families |
Intercrine alpha (chemokine CxC) family |
Paythway |
Chemokinesignalingpathway |
Tag Information |
Tag-Free |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.