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Recombinant Mouse Fatty acid-binding protein, liver protein(Fabp1) (Active)

Recombinant Mouse Fatty acid-binding protein, liver protein(Fabp1) (Active)

Item no.	CSB-AP000551MO-500
Manufacturer	Cusabio
Amount	500ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized powder
Specific against	Mouse
Purity	>95% as determined by SDS-PAGE and HPLC.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Classification	Others
Subdivision	Others
Research Areas	Signal Transduction
Uniprot NO.	P12710
Uniprot Entry Name	FABPL_MOUSE
Gene Names	Fabp1, Fabpl
Source	E.Coli
Expression Region	1-127aa
Sequence	MNFSGKYQLQ SQENFEPFMK AIGLPEDLIQ KG KDIKGVSE IVHEGKKIKL TITYGPKVVR NEFT LGEECE LETMTGEKVK AVVKLEGDNK MVTTFK GIKS VTELNGDTIT NTMTLGDIVY KRVSKRI
Protein Description	Full Length
Tag Info	Tag-Free
Mol. Weight	14.2 kDa
Biological Activity	Fully biologically active when compared to standard. The binding affinity of rMuFABP1 for the synthetic ligand cis-parinaric acid has been measured by fluorescence titration. Half maximal fluorescence of 2.5 uM rMuFABP1 is achieved with approximately 5 uM cis-paranaric acid.
Purity	>95% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered 20 mM PB, pH 7.4, 150mM NaCl , lyophilized
Alias	14 kDa selenium-binding protein, Liver-type fatty acid-binding protein, L-FABP
Relevance	Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Also seems to bind selenium.
PubMed ID	15489334; 2760043; 21183079; 23806337; 23576753
Function	Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
Subcellular Location	Cytoplasm
Protein Families	Calycin superfamily, Fatty-acid binding protein (FABP) family
Tag Information	Tag-Free

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CSB-AP000551MO-500-datasheet.pdf

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