Item no. |
CSB-AP000551MO-500 |
Manufacturer |
Cusabio
|
Amount |
500ug |
Category |
|
Type |
Proteins Recombinant |
Format |
Lyophilized powder |
Specific against |
Mouse |
Purity |
>95% as determined by SDS-PAGE and HPLC. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Available |
|
Classification |
Others |
Subdivision |
Others |
Research Areas |
Signal Transduction |
Uniprot NO. |
P12710 |
Uniprot Entry Name |
FABPL_MOUSE |
Gene Names |
Fabp1, Fabpl |
Source |
E.Coli |
Expression Region |
1-127aa |
Sequence |
MNFSGKYQLQ SQENFEPFMK AIGLPEDLIQ KG KDIKGVSE IVHEGKKIKL TITYGPKVVR NEFT LGEECE LETMTGEKVK AVVKLEGDNK MVTTFK GIKS VTELNGDTIT NTMTLGDIVY KRVSKRI |
Protein Description |
Full Length |
Tag Info |
Tag-Free |
Mol. Weight |
14.2 kDa |
Biological Activity |
Fully biologically active when compared to standard. The binding affinity of rMuFABP1 for the synthetic ligand cis-parinaric acid has been measured by fluorescence titration. Half maximal fluorescence of 2.5 uM rMuFABP1 is achieved with approximately 5 uM cis-paranaric acid. |
Purity |
>95% as determined by SDS-PAGE and HPLC. |
Endotoxin |
Less than 1.0 EU/ug as determined by LAL method. |
Storage Buffer |
0.2 um filtered 20 mM PB, pH 7.4, 150mM NaCl , lyophilized |
Alias |
14 kDa selenium-binding protein, Liver-type fatty acid-binding protein, L-FABP |
Relevance |
Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Also seems to bind selenium. |
PubMed ID |
15489334; 2760043; 21183079; 23806337; 23576753 |
Function |
Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. |
Subcellular Location |
Cytoplasm |
Protein Families |
Calycin superfamily, Fatty-acid binding protein (FABP) family |
Tag Information |
Tag-Free |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.