Item no. |
CSB-AP003241MOW-500 |
Manufacturer |
Cusabio
|
Amount |
500ug |
Category |
|
Type |
Proteins Recombinant |
Format |
Lyophilized powder |
Specific against |
Monkey |
Purity |
>97% as determined by SDS-PAGE and HPLC. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Available |
|
Classification |
Cytokine |
Subdivision |
Interferon |
Research Areas |
Immunology |
Uniprot NO. |
P63310 |
Uniprot Entry Name |
IFNG_MACMU |
Gene Names |
IFNG |
Source |
E.Coli |
Expression Region |
24-165aa |
Sequence |
QDPYVKEAEN LKKYFNAGDP DVADNGTLFL DI LRNWKEES DRKIMQSQIV SFYFKLFKNF KDDQ RIQKSV ETIKEDINVK FFNSNKKKRD DFEKLT NYSV TDSNVQRKAV HELIQVMAEL SPAAKIGK RK RSQMFRGRRA SQ |
Protein Description |
Full Length of Mature Protein |
Tag Info |
Tag-Free |
Mol. Weight |
16.8 kDa |
Biological Activity |
Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using human HeLa cells infected with encephalomyocarditis (EMC) virus is less than 20.0 ng/ml, corresponding to a specific activity of ? 5.0 x104 IU/mg. |
Purity |
>97% as determined by SDS-PAGE and HPLC. |
Endotoxin |
Less than 1.0 EU/ug as determined by LAL method. |
Storage Buffer |
0.2 um filtered PBS, pH 7.4 , lyophilized |
Alias |
IFN-gamma, |
Relevance |
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
PubMed ID |
7561102; 12573592 |
Function |
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
Subcellular Location |
Secreted |
Protein Families |
Type II (or gamma) interferon family |
Tissue Specificity |
Released primarily from activated T lymphocytes. |
Tag Information |
Tag-Free |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.