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Recombinant Rhesus Macaque Interferon gamma protein(IFNG) (Active)

Recombinant Rhesus Macaque Interferon gamma protein(IFNG) (Active)

Item no.	CSB-AP003241MOW-500
Manufacturer	Cusabio
Amount	500ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized powder
Specific against	Monkey
Purity	>97% as determined by SDS-PAGE and HPLC.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Classification	Cytokine
Subdivision	Interferon
Research Areas	Immunology
Uniprot NO.	P63310
Uniprot Entry Name	IFNG_MACMU
Gene Names	IFNG
Source	E.Coli
Expression Region	24-165aa
Sequence	QDPYVKEAEN LKKYFNAGDP DVADNGTLFL DI LRNWKEES DRKIMQSQIV SFYFKLFKNF KDDQ RIQKSV ETIKEDINVK FFNSNKKKRD DFEKLT NYSV TDSNVQRKAV HELIQVMAEL SPAAKIGK RK RSQMFRGRRA SQ
Protein Description	Full Length of Mature Protein
Tag Info	Tag-Free
Mol. Weight	16.8 kDa
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using human HeLa cells infected with encephalomyocarditis (EMC) virus is less than 20.0 ng/ml, corresponding to a specific activity of ? 5.0 x104 IU/mg.
Purity	>97% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Alias	IFN-gamma,
Relevance	Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
PubMed ID	7561102; 12573592
Function	Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Subcellular Location	Secreted
Protein Families	Type II (or gamma) interferon family
Tissue Specificity	Released primarily from activated T lymphocytes.
Tag Information	Tag-Free

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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