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Recombinant Human Tumor necrosis factor ligand superfamily member 9 protein(TNFSF9) (Active)

Recombinant Human Tumor necrosis factor ligand superfamily member 9 protein(TNFSF9) (Active)

Item no.	CSB-AP001961HU-500
Manufacturer	Cusabio
Amount	500ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized powder
Specific against	Human
Purity	>95% as determined by SDSPAGE and HPLC.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Classification	Cytokine
Subdivision	Tumor Necrosis Factor
Research Areas	Cancer
Uniprot NO.	P41273
Uniprot Entry Name	TNFL9_HUMAN
Gene Names	TNFSF9
Source	E.Coli
Expression Region	71-254aa
Sequence	REGPELSPDD PAGLLDLRQG MFAQLVAQNV LL IDGPLSWY SDPGLAGVSL TGGLSYKEDT KELV VAKAGV YYVFFQLELR RVVAGEGSGS VSLALH LQPL RSAAGAAALA LTVDLPPASS EARNSAFG FQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE
Protein Description	Partial
Tag Info	Tag-Free
Mol. Weight	19.4 kDa
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL8 production using human PBMC is less than 10 ng/ml, corresponding to a specific activity of ? 1.0 x 105 IU/mg.
Purity	>95% as determined by SDSPAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Alias	4-1BB ligand,
Relevance	Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. {ECO:0000269\|PubMed:20032458}.
PubMed ID	8088337; 15489334; 20032458
Function	Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
Subcellular Location	Membrane, Single-pass type II membrane protein
Protein Families	Tumor necrosis factor family
Tissue Specificity	Expressed in brain, placenta, lung, skeletal muscle and kidney.
Tag Information	Tag-Free

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