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Recombinant Human Interleukin-3 protein(IL3) (Active)

Recombinant Human Interleukin-3 protein(IL3) (Active)

Item no.	CSB-AP001701HU-1
Manufacturer	Cusabio
Amount	1mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized powder
Specific against	Human
Purity	>96% as determined by SDS-PAGE and HPLC.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Classification	Cytokine
Subdivision	Interleukin
Research Areas	Immunology
Uniprot NO.	P08700
Uniprot Entry Name	IL3_HUMAN
Gene Names	IL3
Source	E.Coli
Expression Region	20-152aa
Sequence	APMTQTTSLK TSWVNCSNMI DEIITHLKQP PL PLLDFNNL NGEDQDILME NNLRRPNLEA FNRA VKSLQN ASAIESILKN LLPCLPLATA APTRHP IHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTL SL AIF
Protein Description	Full Length of Mature Protein
Tag Info	Tag-Free
Mol. Weight	15.0 kDa
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1 ng/ml, corresponding to a specific activity of ? 1.0 x 107 IU/mg.
Purity	>96% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Alias	IL-3, Mast cell growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor
Relevance	Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.; This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
PubMed ID	3497843; 3127463; 3489530; 15372022; 15489334; 2544122; 8676386
Function	Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.; FUNCTION
Subcellular Location	Secreted
Protein Families	IL-3 family
Tissue Specificity	Activated T-cells, mast cells, natural killer cells.
Paythway	Jak-STATsignalingpathway
Tag Information	Tag-Free

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CSB-AP001701HU-1-datasheet.pdf

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