Item no. |
CSB-PA887033LC01HU |
Manufacturer |
Cusabio
|
Amount |
100ug |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
N-acetyltransferase 8 (EC:2.3.1.-),NAT8,Acetyltransferase 2,ATase2,Camello-like protein 1,Cysteinyl-conjugate N-acetyltransferase (EC:2.3.1.80),CCNAT |
Available |
|
Background |
Acetylates the free alpha-amino group of cysteine S-conjugates to form mercapturic acids (PubMed:20392701). This is the final step in a major route for detoxification of a wide variety of reactive electrophiles which starts with their incorporation into glutathione S-conjugates. The glutathione S-conjugates are then further processed into cysteine S-conjugates and finally mercapturic acids which are water soluble and can be readily excreted in urine or bile. Alternatively, may have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1 (PubMed:24556617). May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (PubMed:19011241). |
Alias |
N-acetyltransferase 8 (EC:2.3.1.-), NAT8, Acetyltransferase 2, ATase2, Camello-like protein 1, Cysteinyl-conjugate N-acetyltransferase (EC:2.3.1.80), CCNAT |
Uniprot |
Q9UHE5 |
Immuongen |
Recombinant human N-acetyltransferase 8 protein (64-227AA) |
Counjugation |
FITC |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Storage |
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze. |
Purification |
Caprylic Acid Ammonium Sulfate Precipitation purified |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.