Item no. |
CSB-PA622686LB01HU |
Manufacturer |
Cusabio
|
Amount |
100ug |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2,hBACURD2,BTB/POZ domain-containing protein TNFAIP1,Protein B12,Tumor necrosis factor,alpha-induced protein 1,endothelial,TNFAIP1,BACURD2,EDP1 |
Available |
|
Background |
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity. |
Alias |
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2, hBACURD2, BTB/POZ domain-containing protein TNFAIP1, Protein B12, Tumor necrosis factor, alpha-induced protein 1, endothelial, TNFAIP1, BACURD2, EDP1 |
Uniprot |
Q13829 |
Immuongen |
Recombinant Human BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 protein (233-316AA) |
Counjugation |
HRP |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Storage |
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze. |
Purification |
>95%, Protein G purified |
Abbreviation |
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.