Item no. |
CSB-PA07427A0Rb |
Manufacturer |
Cusabio
|
Amount |
100ug |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Cachectin
TNF-alpha
Tumor necrosis factor ligand superfamily member 2
TNF
TNFA, TNFSF2 |
Available |
|
Uniprot ID |
P01375 |
Immunogen |
Recombinant Human Tumor necrosis factor protein |
Conjugate |
Non-conjugated |
Alias |
Cachectin TNF-alpha Tumor necrosis factor ligand superfamily member 2 TNF TNFA, TNFSF2 |
Relevance |
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. |
Buffer |
Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Form |
Liquid |
Stroage |
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze. |
Purity |
Caprylic Acid Ammonium Sulfate Precipitation purified |
Research Area |
Immunology |
References |
Tandem arrangement of genes coding for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) in the human genome.Nedospasov S.A., Shakhov A.N., Turetskaya R.L., Mett V.A., Azizov M.M., Georgiev G.P., Korobko V.G., Dobrynin V.N., Filippov S.A., B |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.