Item no. |
CSB-PA023386ESR2HU |
Manufacturer |
Cusabio
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
liquid |
Applications |
WB, IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
NIMA-interacting protein 2,TTAGGG repeat-binding factor 1,Telomeric protein Pin2/TRF1,TERF1,PIN2, TRBF1, TRF, TRF1 |
Available |
|
Alias |
NIMA-interacting protein 2, TTAGGG repeat-binding factor 1, Telomeric protein Pin2/TRF1, TERF1, PIN2, TRBF1, TRF, TRF1 |
Uniprot ID |
P54274 |
Immunogen |
Recombinant human Telomeric repeat-binding factor 1 protein (260-439aa) |
Tested applications |
ELISA, WB, IHC; Recommended dilution:WB:1:200-1000, IHC:1:20-1:200 |
Background |
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. |
Conjugate |
Non-conjugated |
Stroage Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Stroage |
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze. |
Purity |
Antigen Affinity Purified |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.