Item no. |
CSB-PA022389EA01HU |
Manufacturer |
Cusabio
|
Amount |
100ug |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
IF, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Suppressor of cytokine signaling 2,SOCS-2,Cytokine-inducible SH2 protein 2,CIS-2,STAT-induced STAT inhibitor 2,SSI-2,SOCS2,CIS2,SSI2,STATI2 |
Available |
|
Background |
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
Alias |
Suppressor of cytokine signaling 2, SOCS-2, Cytokine-inducible SH2 protein 2, CIS-2, STAT-induced STAT inhibitor 2, SSI-2, SOCS2, CIS2, SSI2, STATI2 |
Uniprot |
O14508 |
Immuongen |
Recombinant Human Suppressor of cytokine signaling 2 protein (1-198AA) |
Counjugation |
Non-conjugated |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Storage |
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze. |
Purification |
>95%, Protein G purified |
Abbreviation |
Suppressor of cytokine signaling 2 |
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