Item no. |
CSB-PA007876LA01HU-50ug |
Manufacturer |
Cusabio
|
Amount |
50ug |
Quantity options |
100ug
20ug
50ug
|
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
exo1 antibody; EXO1_HUMAN antibody; ExoI antibody; Exonuclease 1 antibody; Exonuclease I antibody; Exonuclease1 antibody; HEX1 antibody; hExo I antibody; hExo1 antibody; hExoI antibody; Rad2 nuclease family member homolog of S. cerevisiae exonuclease 1 antibody, Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI), EXO1, EXOI HEX1 |
Similar products |
EXO1, Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI), EXOI HEX1 |
Available |
|
Immunogen Species |
Human |
UniprotID |
Q9UQ84 |
Immunogen |
Recombinant Human Exonuclease 1 protein (301-600AA) |
Applications info |
ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
Dilution ratio 1 |
ELISA:1:2000-1:10000 |
Dilution ratio 2 |
WB:1:1000-1:5000 |
Dilution ratio 3 |
IHC:1:20-1:200 |
Background |
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis. |
Conjugate |
Non-conjugated |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
>95%, Protein G purified |
General Research Areas |
Epigenetics and Nuclear Signaling |
Initial Research Areas |
Epigenetics and Nuclear Signaling |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.