Comparison

Recombinant Human Interleukin 8 (a. a. 77)

Item no. DAG352
Manufacturer Creative Diagnostics
Amount 25ug
Category
Type Proteins Recombinant
Format Purified, Lyophilized
Specific against Human
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Available
Abbr
IL8
Full name
Interleukin 8
Product Overview
RecombinantHuman Interleukin-8 (IL-8), 8.9kDa Endothelial IL-8 is an 8.9kDa proteincontaining 77 amino acid residues, was expressed in E. coli. It promotesneutrophil chemotaxis and degranulation. The 77 amino acid IL-8 is thepredominant form secreted by endothelial cells.
Antigen Description
Interleukin-8 (IL-8) is a chemokine produced by macrophages andother cell types such as epithelial cells. It is also synthesized byendothelial cells, which store IL-8 in their storage vesicles, theWeibel-Palade bodies. In humans, the interleukin-8 protein is encoded by theIL8 gene.
Source
E. coli
Format
Purified, Lyophilized. We recommend a quick spin followed byreconstitution in water to a concentration of 0.1-1.0mg/ml. This solution canthen be diluted into other buffered solutions and stored (up to 1 week) at2-8C or stored at –20C for future use.
Buffer
Notapplicable
Concentration
Notapplicable.
Purification
>98% pure (SDS-PAGE and HPLC analysis). Endotoxin level is<0.1ng per ug (1EU/ug).
Applications
Biological activity was determined by its ability tochemoattract human peripheral blood neutrophils using a concentration of25.0-150.0ng/ml. Each laboratory should determine an optimum working titerfor use in its particular application. Other applications have not beentested but use in such assays should not necessarily be excluded.
Preservative
None
Storage
The lyophilized product is stable for a few weeks at roomtemperature but is best stored at –20oC. After reconstitution, aliquot andstore at –20oC.
Gene Information - Gene Name
IL8interleukin 8 [ Homo sapiens ]
Gene Information - Synonyms
IL8, interleukin 8, NAF, GCP1, LECT, LUCT, NAP1, CXCL8, GCP-1, LYNAP, MDNCF, MONAP, NAP-1, emoctakin, OTTHUMP00000199824, OTTHUMP00000199825, neutrophil-activating peptide 1, chemokine (C-X-C motif) ligand 8, beta-thromboglobulin-like protein, granulocyte chemotactic protein 1, tumornecrosis factor-induced gene 1, alveolar macrophage chemotactic factor I, monocyte-derived neutrophil chemotactic factor, GCP/IL-8 protein I, GCP/IL-8protein II, GCP/IL-8 protein III, GCP/IL-8 protein IV, GCP/IL-8 protein V, GCP/IL-8 protein VI, Granulocyte chemotactic protein 1, IL-8(1-77), IL8/NAP1form I, IL8/NAP1 form II, IL8/NAP1 form III, IL8/NAP1 form IV, IL8/NAP1 formV, IL8/NAP1 form VI, K 60, MDNCF-b, MDNCF-c, Lymphocyte derived neutrophilactivating factor, NAF, Neutrophil-activating protein 1, Protein 3-10C, SCYB8, Small inducible cytokine subfamily B member 8, TSG 1, T cell chemotacticfactor
Gene Information - GeneID
3576
Gene Information - mRNA Refseq
NM_000584
Gene Information - Protein Refseq
NP_000575
Gene Information - MIM
146930
Gene Information - UniProt ID
P10145
Gene Information - Pathway
ATF-2transcription factor network, Chagas disease (American trypanosomiasis), Epithelial cell signaling in Helicobacter pylori infection, Legionellosis, Malaria
Gene Information - Function
chemokineactivity, interleukin-8 receptor binding, protein binding

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25ug
Available: In stock
available

Delivery expected until 10/4/2024 

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