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SK-BR-3 cells

SK-BR-3 cells

Item no.	C0006007
Manufacturer	Addexbio
Amount	One Frozen vial
Category	Oncology Food Safety Hormones Metabolism Diabetes Cell Lines & Cell Culture Cell Lines By Organ Lung Cancer Skin Cancer Breast Cancer
Type	Tumour Cells
Specific against	Human (Homo sapiens)
Dry ice	Yes
Citations	1.Brockhoff, G., Heckel, B., Schmidt-Bruecken, E., Plander, M., Hofstaedter, F., Vollmann, A., and Diermeier, S. Differential impact of Cetuximab, Pertuzumab and Trastuzumab on BT474 and SK-BR-3 breast cancer cell proliferation. Cell Prolif, 40: 488-507, 2007. 2.Choi, E. J. and Kim, G. H. Apigenin causes G(2)/M arrest associated with the modulation of p21(Cip1) and Cdc2 and activates p53-dependent apoptosis pathway in human breast cancer SK-BR-3 cells. J Nutr Biochem, 20: 285-290, 2009. 3.Hill, A. A., LaPan, P., Li, Y., and Haney, S. Impact of image segmentation on high-content screening data quality for SK-BR-3 cells. BMC Bioinformatics, 8: 340, 2007. 4.Koster, F., Felberbaum, R., Finas, D., Wunsch, K., Schulz, C., Diedrich, K., and Hauser, C. Progesterone and estradiol enhance lipid mediated transfection of Sk-Br-3 mammalian cancer cells. Int J Mol Med, 9: 617-620, 2002. 5.Lin, Y. J., Huang, Y. H., Zhen, Y. Z., Liu, X. J., and Zhen, Y. S. [Rhein lysinate induces apoptosis in breast cancer SK-Br-3 cells by inhibiting HER-2 signal pathway]. Yao Xue Xue Bao, 43: 1099-1105, 2008. 6.Manfroid, I., Van de Weerdt, C., Baudhuin, A., Martial, J. A., and Muller, M. EGF stimulates Pit-1 independent transcription of the human prolactin pituitary promoter in human breast cancer SK-BR-3 cells through its proximal AP-1 response element. Mol Cell Endocrinol, 229: 127-139, 2005.
ECLASS 10.1	32160890
ECLASS 11.0	32160890
UNSPSC	41106509
Available
Description	Disease: Breast adenocarcinoma Origin: Pleural effusion Species: Homo sapiens Tissue: Breast; mammary gland Morphology: Epithelial Properties: Adherent Cytogenic data: This is a hypertriploid to hypotetraploid human cell line(+A, +B, +C, +E, +F, +G, -D) with abnormalities including dicentrics, acrocentric fragments, rings, secondary constrictions, large metacentrics or polycentrics and large submetacentric marker Patient: Female, Caucasian, 43 yrs of age Medium: McCoy's 5a (Gibco 16600082) + 10% FBS Subculture: 1:2 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37 C Freezing Medium: Complete culture medium supplemented with 5% (v/v) DMSO Biosafety Level: I Sterility: Bacteria: Negative Yeast: Negative Mycoplasma: Negative Pathogens: HIV: Negative Hepatitis B: Negative Hepatitis C: Negative Protein Expression: HER2/c-erb-2 Isoenzymes: AK-1, 1-2; ES-D, 1; G6PD, B; GLO-I, 2; PGM1, 1-2; PGM3, 1 DNA Profile (STR): Amelogenin: X CSF1PO: 12 D13S317: 11, 12 D16S539: 9 D5S818: 9, 12 D7S820: 9, 12 THO1: 8, 9 TPOX: 8, 11 vWA: 17 Citation Format: If use of this culture results in a scientific publication, it should be cited in the publication as: SK-BR-3 (AddexBio C0006007) Mutations in SK-BR-3 Cells Related cells by Organ: 4T1 AU-565 BT-20 BT-474 BT-483 BT-549 JIMT-1 MCF-7 SK-BR-3 T47D ZR-75-1
Storage condition	LN2
Manufacturers Category	Cell Lines

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: One Frozen vial

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