Comparison

SK-BR-3 cells

Item no. C0006007
Manufacturer Addexbio
Amount One Frozen vial
Category
Type Tumour Cells
Specific against Human
Dry ice Yes
Citations 1.Brockhoff, G., Heckel, B., Schmidt-Bruecken, E., Plander, M., Hofstaedter, F., Vollmann, A., and Diermeier, S. Differential impact of Cetuximab, Pertuzumab and Trastuzumab on BT474 and SK-BR-3 breast cancer cell proliferation. Cell Prolif, 40: 488-507, 2007.
2.Choi, E. J. and Kim, G. H. Apigenin causes G(2)/M arrest associated with the modulation of p21(Cip1) and Cdc2 and activates p53-dependent apoptosis pathway in human breast cancer SK-BR-3 cells. J Nutr Biochem, 20: 285-290, 2009.
3.Hill, A. A., LaPan, P., Li, Y., and Haney, S. Impact of image segmentation on high-content screening data quality for SK-BR-3 cells. BMC Bioinformatics, 8: 340, 2007.
4.Koster, F., Felberbaum, R., Finas, D., Wunsch, K., Schulz, C., Diedrich, K., and Hauser, C. Progesterone and estradiol enhance lipid mediated transfection of Sk-Br-3 mammalian cancer cells. Int J Mol Med, 9: 617-620, 2002.
5.Lin, Y. J., Huang, Y. H., Zhen, Y. Z., Liu, X. J., and Zhen, Y. S. [Rhein lysinate induces apoptosis in breast cancer SK-Br-3 cells by inhibiting HER-2 signal pathway]. Yao Xue Xue Bao, 43: 1099-1105, 2008.
6.Manfroid, I., Van de Weerdt, C., Baudhuin, A., Martial, J. A., and Muller, M. EGF stimulates Pit-1 independent transcription of the human prolactin pituitary promoter in human breast cancer SK-BR-3 cells through its proximal AP-1 response element. Mol Cell Endocrinol, 229: 127-139, 2005.
ECLASS 10.1 32160890
ECLASS 11.0 32160890
UNSPSC 41106509
Available
Description

Disease:

Breast adenocarcinoma

Origin:

Pleural effusion

Species:

Homo sapiens

Tissue:

Breast; mammary gland

Morphology:

Epithelial

Properties:

Adherent

Cytogenic data:

This is a hypertriploid to hypotetraploid human cell line(+A, +B, +C, +E, +F, +G, -D) with abnormalities including dicentrics, acrocentric fragments, rings, secondary constrictions, large metacentrics or polycentrics and large submetacentric marker

Patient:

Female, Caucasian, 43 yrs of age

Medium:

McCoy's 5a (Gibco 16600082) + 10% FBS

Subculture:

1:2 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37 C

Freezing Medium:

Complete culture medium supplemented with 5% (v/v) DMSO

Biosafety Level:

I

Sterility:

Bacteria: Negative

Yeast: Negative

Mycoplasma: Negative

Pathogens:

HIV: Negative

Hepatitis B: Negative

Hepatitis C: Negative

Protein Expression:

HER2/c-erb-2

Isoenzymes:

AK-1, 1-2; ES-D, 1; G6PD, B; GLO-I, 2; PGM1, 1-2; PGM3, 1

DNA Profile (STR):

Amelogenin: X

CSF1PO: 12

D13S317: 11, 12

D16S539: 9

D5S818: 9, 12

D7S820: 9, 12

THO1: 8, 9

TPOX: 8, 11

vWA: 17

Citation Format:

If use of this culture results in a scientific publication, it should be cited in the publication as: SK-BR-3 (AddexBio C0006007)

Mutations in SK-BR-3 Cells

Related cells by Organ:

4T1

AU-565

BT-20

BT-474

BT-483

BT-549

JIMT-1

MCF-7

SK-BR-3

T47D

ZR-75-1

Storage condition
LN2
Manufacturers Category
Cell Lines

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: One Frozen vial
Available: In stock
available

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