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T47D cells

T47D cells

Item no.	C0006001
Manufacturer	Addexbio
Amount	One Frozen vial
Category	Oncology Food Safety Hormones Neuroscience Metabolism Diabetes Neural Signaling Cell Lines & Cell Culture Cell Lines By Organ Skin Cancer Breast Cancer Testicular & Prostate Cancer
Type	Tumour Cells
Specific against	Human
Dry ice	Yes
Citations	1.Afhuppe, W., Sommer, A., Muller, J., Schwede, W., Fuhrmann, U., and Moller, C. Global gene expression profiling of progesterone receptor modulators in T47D cells provides a new classification system. J Steroid Biochem Mol Biol, 113: 105-115, 2009. 2.Chen, Y., Huang, K., Chen, K. E., and Walker, A. M. Prolactin and estradiol utilize distinct mechanisms to increase serine-118 phosphorylation and decrease levels of estrogen receptor alpha in T47D breast cancer cells. Breast Cancer Res Treat, 120: 369-377. 3.Holley, A. K., Kiningham, K. K., Spitz, D. R., Edwards, D. P., Jenkins, J. T., and Moore, M. R. Progestin stimulation of manganese superoxide dismutase and invasive properties in T47D human breast cancer cells. J Steroid Biochem Mol Biol, 117: 23-30, 2009. 4.Hua, D., Chen, B., Bai, M., Yu, H., Wu, X., and Jin, W. PEA3 activates VEGF transcription in T47D and SKBR3 breast cancer cells. Acta Biochim Biophys Sin (Shanghai), 41: 63-68, 2009. 5.Sanada, N., Gotoh, Y., Shimazawa, R., Klinge, C. M., and Kizu, R. Repression of activated aryl hydrocarbon receptor-induced transcriptional activation by 5alpha-dihydrotestosterone in human prostate cancer LNCaP and human breast cancer T47D cells. J Pharmacol Sci, 109: 380-387, 2009. 6.Zhang, Y., Zhao, H., Asztalos, S., Chisamore, M., Sitabkhan, Y., and Tonetti, D. A. Estradiol-induced regression in T47D:A18/PKCalpha tumors requires the estrogen receptor and interaction with the extracellular matrix. Mol Cancer Res, 7: 498-510, 2009.
ECLASS 10.1	32160890
ECLASS 11.0	32160890
UNSPSC	41106509
Available
Description	Disease: Breast ductal carcinoma Origin: Derived from metastatic pleural effusion Species: Homo sapiens Tissue: Breast Morphology: Epithelial Properties: Adherent Cytogenic data: This is a hypotriploid human cell line Patient: Female, 54 yrs of age Medium: AddexBio-formulated RPMI-1640 Medium(C0004-01) + 10% FBS Subculture: 1:3 to 1:5 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37C Freezing Medium: Complete culture medium supplemented with 5% (v/v) DMSO Biosafety Level: I Sterility: Bacteria: Negative Yeast: Negative Mycoplasma: Negative Pathogens: HIV: Negative Hepatitis B: Negative Hepatitis C: Negative Protein Expression: calcitonin, androgen receptor, estrogen receptor, progesterone receptor, glucocorticoid receptor, prolactin, Isoenzymes: AK-1, 1; ES-D, 2; G6PD, B; GLO-I, 1-2; PGM1, 1; PGM3, 1 DNA Profile (STR): Amelogenin: X CSF1PO: 11, 13 D13S317: 12 D16S539: 10 D5S818: 12 D7S820: 11 THO1: 6 TPOX: 11 vWA: 14 Citation Format: If use of this culture results in a scientific publication, it should be cited in the publication as: T47D (AddexBio C0006001) Mutations in T47D Cells Related cells by Organ: 4T1 AU-565 BT-20 BT-474 BT-483 BT-549 JIMT-1 MCF-7 SK-BR-3 T47D ZR-75-1
Storage condition	LN2
Manufacturers Category	Cell Lines

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: One Frozen vial

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