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5637 cells

5637 cells

Item no.	C0002001
Manufacturer	Addexbio
Amount	One Frozen vial
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Neural Signaling Cell Lines & Cell Culture Cell Lines By Organ Skin Cancer Bladder Cancer Testicular & Prostate Cancer
Type	Tumour Cells
Specific against	Human (Homo sapiens)
Dry ice	Yes
Citations	1.Baierlein SA, Distel L, Sieber R, Weiss C, Rodel C, Sauer R, and Rodel F. Combined effect of tumor necrosis factor-alpha and ionizing radiation on the induction of apoptosis in 5637 bladder carcinoma cells. Strahlenther Onkol 182: 467-472, 2006. 2.Cheng G and Xie L. Parthenolide induces apoptosis and cell cycle arrest of human 5637 bladder cancer cells in vitro. Molecules 16: 6758-6768, 2010. 3.Lee SJ, Cho YH, Park K, Kim EJ, Jung KH, Park SS, Kim WJ, and Moon SK. Magnolol elicits activation of the extracellular signal-regulated kinase pathway by inducing p27KIP1-mediated G2/M-phase cell cycle arrest in human urinary bladder cancer 5637 cells. Biochem Pharmacol 75: 2289-2300, 2008. 4.Lee SJ, Cho YH, Park K, Kim EJ, Kang BS, Jung KH, Kim CH, Kim WJ, and Moon SK. Inhibitory effects of the aqueous extract of Magnolia officinalis on the responses of human urinary bladder cancer 5637 cells in vitro and mouse urinary bladder tumors induced by N-Butyl-N-(4-hydroxybutyl) nitrosamine in vivo. Phytother Res 23: 20-27, 2009. 5.Lee SJ, Kim HM, Cho YH, Park K, Kim EJ, Jung KH, Kim CH, Kim WJ, and Moon SK. Aqueous extract of Magnolia officinalis mediates proliferative capacity, p21WAF1 expression and TNF-alpha-induced NF-kappaB activity in human urinary bladder cancer 5637 cells; involvement of p38 MAP kinase. Oncol Rep 18: 729-736, 2007. 6.Lee SJ, Park SS, Lee US, Kim WJ, and Moon SK. Signaling pathway for TNF-alpha-induced MMP-9 expression: mediation through p38 MAP kinase, and inhibition by anti-cancer molecule magnolol in human urinary bladder cancer 5637 cells. Int Immunopharmacol 8: 1821-1826, 2008. 7.Mao Q, Li Y, Zheng X, Yang K, Shen H, Qin J, Bai Y, Kong D, Jia X, and Xie L. Up-regulation of E-cadherin by small activating RNA inhibits cell invasion and migration in 5637 human bladder cancer cells. Biochem Biophys Res Commun 375: 566-570, 2008. 8.Matin SF, Rackley RR, Sadhukhan PC, Kim MS, Novick AC, and Bandyopadhyay SK. Impaired alpha-interferon signaling in transitional cell carcinoma: lack of p48 expression in 5637 cells. Cancer Res 61: 2261-2266, 2001. 9.Mills M, Meysick KC, and O'Brien AD. Cytotoxic necrotizing factor type 1 of uropathogenic Escherichia coli kills cultured human uroepithelial 5637 cells by an apoptotic mechanism. Infect Immun 68: 5869-5880, 2000. 10.Monami G, Gonzalez EM, Hellman M, Gomella LG, Baffa R, Iozzo RV, and Morrione A. Proepithelin promotes migration and invasion of 5637 bladder cancer cells through the activation of ERK1/2 and the formation of a paxillin/FAK/ERK complex. Cancer Res 66: 7103-7110, 2006. 11.Plattner VE, Wagner M, Ratzinger G, Gabor F, and Wirth M. Targeted drug delivery: binding and uptake of plant lectins using human 5637 bladder cancer cells. Eur J Pharm Biopharm 70: 572-576, 2008. 12.Rassouli FB, Matin MM, Iranshahi M, Bahrami AR, Behravan J, Mollazadeh S, Neshati V, and Kalalinia F. Investigating the enhancement of cisplatin cytotoxicity on 5637 cells by combination with mogoltacin. Toxicol In Vitro 25: 469-474, 2010.
ECLASS 10.1	32160890
ECLASS 11.0	32160890
UNSPSC	41106509
Available
Description	Disease: Urinary bladder carcinoma Origin: Established from the primary bladder carcinoma (grade II) of a patient Species: Homo sapiens Tissue: Bladder (urinary) Morphology: Epithelial Properties: Adherent Cytogenic data: Tumorigenic Patient: Male, Caucasian, 68 yrs of age Medium: AddexBio-formulated RPMI-1640 Medium(C0004-01) + 10% FBS Subculture: 1:5 to 1:8 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37C Freezing Medium: Complete culture medium supplemented with 5% (v/v) DMSO Biosafety Level: I Sterility: Bacteria: Negative Yeast: Negative Mycoplasma: Negative Pathogens: HIV: Negative Hepatitis B: Negative Hepatitis C: Negative Isoenzymes: AK-1, 1; ES-D, 1; G6PD, B; GLO-I, 1-2; Me-2, 1; PGM1, 1; PGM3, 2 DNA Profile (STR): Amelogenin: X, Y CSF1PO: 11 D13S317: 11 D16S539: 9 D5S818: 11, 12 D7S820: 10, 11 THO1: 7, 9 TPOX: 8, 9 vWA: 16, 18 D3S1358: 15, 17 D21S11: 36 D18S51: 16, 18 Penta E: 10, 12 Penta D: 11 D8S1179: 10, 11 FGA: 22 Citation Format: If use of this culture results in a scientific publication, it should be cited in the publication as: 5637 (AddexBio C0002001) Mutations in 5637 Cells
Storage condition	LN2
Manufacturers Category	Cell Lines

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: One Frozen vial

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