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Recombinant ICDH

Recombinant ICDH

Item no.	CS-CSI12689
Manufacturer	Cell Sciences
Amount	5 mg
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Necrosis Myelofibrosis Astrocytoma By Organ Brain Cancer
Type	Proteins
Specific against	other
Purity	Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	IDH, IDP, Cytosolic NADP-isocitrate dehydrogenase, Isocitrate dehydrogenase [NADP] cytoplasmic, Oxalosuccinate decarboxylase, PICD., NADP(+)-specific ICDH, EC 1.1.1.42
Available
Biological Activity	The specific activity was found to be 119 U/mg.
Description	Isocitrate Dehydrogenase is an enzyme of the oxidoreductase class that catalyzes the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires Mg2+, Mn2+, it is activated by ADP, citrate, and Ca2+, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. The ICDH is purified by proprietary chromatographic techniques.
Formulation	One ml of solution (1 mg/340 ul) contains 0.075 mol/l KPO4, 50% Glycerol, pH 7.1.
Storage and Stability	ICDH although stable at 15C for 1 week should be stored between 2C-8C. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA) Please avoid freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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