Item no. |
CS-CSI20129B |
Manufacturer |
Cell Sciences
|
Amount |
10 ug |
Category |
|
Type |
Proteins |
Specific against |
Mouse (Murine, Mus musculus) |
Host |
E.coli |
Purity |
>98% by SDS-PAGE and HPLC analyses. |
Sequence |
SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSKI |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
IL-33, C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2, DVS27-related protein, nuclear factor from high endothelial venules, IL-1F11, interleukin-33, interleukin-1 family member 11 |
Available |
|
Biological Activity |
Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay usingmouse D10S cells is less than 0.5 ng/ml |
Description |
Recombinant Mouse Interleukin-33 (IL-33) is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. |
Endotoxin Level |
Less than 1EU/ug of rMuIL-33 as determined by LAL method. |
Formulation |
Lyophilized from a 0.2 um filtered solution in PBS, EDTA and DTT. |
Molecular Weight |
Approximately 17.5 kDa protein containing 158 amino acid residues. |
Reconstitution |
Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions. |
Storage and Stability |
This lyophilized preparation is stable at 2-4C, but should be kept desiccated at -20C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles. |
Specificity |
2 x 106 units/mg |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.