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Recombinant Mouse Thrombopoietin

Recombinant Mouse Thrombopoietin

Item no.	CS-CSI12329
Manufacturer	Cell Sciences
Amount	10 ug
Category	Oncology By Cell Type Hematology Leukemia Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Myelofibrosis By Organ Heart & Blood Cancer
Type	Proteins
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Purity	>98% by SDS-PAGE and HPLC analyses. Endotoxin level is <0.1 ng per ug of TPO.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	TPO, myeloproliferative leukemia virus oncogene ligand, Mpllg, TPO-1, TPO-2, TPO-3, TPO-4, OTTMUSP00000023070, OTTMUSP00000023071
Available
Biological Activity	The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells is < 1.0 ng/ml, corresponding to a specific activity of > 1 x 106 units/mg.
Description	TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets, in vivo . TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and mouse TPO exhibits cross-species reactivity. Recombinant mouse TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.
Formulation	Sterile filtered and lyophilized from 10 mM Tris, pH 8.0.
Molecular Weight	18.7 kDa
Reconstitution	Centrifuge vial prior to opening. The mouse TPO should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20C.
Storage and Stability	The lyophilized TPO should be stored desiccated below 0C. Reconstituted TPO should be stored in working aliquots at -20C. Avoid repeated freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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