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Synthetic Human BACE-2 Blocking Blocking Peptide (aa 44-59)(NT) Blocking Peptide

Synthetic Human BACE-2 Blocking Blocking Peptide (aa 44-59)(NT) Blocking Peptide

Item no.	CS-PX186BP
Manufacturer	Cell Sciences
Amount	50 ug
Category	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding By Cell Type Peptides & Proteins Adenocarcinoma Enzymes Other Fatty Acid Enzymes Peptides
Type	Proteins
Specific against	Human (Homo sapiens)
Sequence	NH2-APTPGPGTPAERHADG-OH
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	AEPLC, ALP56, ASP21, ASP1, BAE2, CDA13, CEAP1, DRAP, 56 kDa aspartic-like protease, Down syndrome region aspartic protease, aspartyl protease 1, beta secretase 2, beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, memapsin-1, membrane-associated aspartic protease 1, transmembrane aspartic proteinase Asp1
Available
Description	Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.
Formulation	It is supplied as 200 ug/ml, 50 ug/vial, in PBS pH7.2 (10 mM NaH2PO4, 10 mM, Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.
Storage and Stability	Store at -20C, stable for one year.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 3/28/2025

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