Similar products |
CD184, LAP3, NPYR, C-X-C chemokine receptor type 4, FB22, HM89, LCR1, NPYRL, LESTR, seven transmembrane helix receptor, D2S201E, HSY3RR, NPY3R, NPYY3R, WHIM, CD184 antigen, fusin, leukocyte-derived seven-transmembrane-domain receptor, chemokine (C-X-C motif), receptor 4 (fusin), chemokine receptor 4, lipopolysaccharide-associated protein 3, neuropeptide Y receptor Y3, seven-transmembrane-segment receptor, spleen, stromal cell-derived factor 1 receptor |
Description |
CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Formulation |
It is supplied as 200 ug/ml, 50 ug/vial, in PBS pH7.2 (10 mM NaH2PO4, 10 mM, Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only. |