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Native Human Alpha-1-Antitrypsin

Native Human Alpha-1-Antitrypsin

Item no.	CS-CSI19775B
Manufacturer	Cell Sciences
Amount	5 mg
Category	Peptides & Proteins Cardiovascular Research Heart Failure Myocardial Infarction Atherosclerosis Hypertension Native Proteins
Type	Proteins
Specific against	Human
Host	Human
Purity	>95% by SDS-PAGE
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	member 1, AAT, PI1, serine (or cysteine) proteinase inhibitor, PI, A1A, A1AT, MGC23330, MGC9222, PRO2275, protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin, clade A, serine proteinase inhibitor
Available
Description	Alpha 1-Antitrypsin (A1AT) is a glycoprotein serine protease inhibitor (serpin), inhibiting a wide variety of proteases. It is an acute phase protein that protects tissues from enzymes of inflammatory cells, especially Elastase. In the absence of A1AT, Elastase is free to break down Elastin, which contributes to the elasticity of the lungs, resulting in respiratory complications such as emphysema, or COPD (chronic obstructive pulmonary disease) in adults and cirrhosis in adults or children.
Formulation	Lyophilized from 0.03 M Sodium Phosphate pH 6.5 + 0.3 M NaCl
Molecular Weight	52 kDa
Storage and Stability	Store at -70C.
Specificity	75-100% inhibitory when tested with active-site titrated porcine pancreatic trypsin using N-Benzoyl-L-Arginine-para-Nitroanilide Hydrochloride (L-BAPNA) as substrate.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CS-CSI19775B-datasheet.pdf

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Amount: 5 mg

available

Delivery expected until 12/13/2024