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Recombinant Human Ras-related protein Rap-1b, C-terminal deletion

Recombinant Human Ras-related protein Rap-1b, C-terminal deletion

Item no.	CS-CSI13790
Manufacturer	Cell Sciences
Amount	50 ug
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cytoskeleton small GTPases Ras Subfamily Rap Subfamily
Type	Proteins
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	> 95% by SDS-PAGE analysis
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	small GTP binding protein, DKFZp586H0723, K-REV, RAL1B, RAS-related protein RAP1B, Ras family small GTP binding protein RAP1B, OTTHUMP00000165026
Available
Concentration	1.0 mg/ml
Description	Rap (Ras-proximate) proteins are GTPases that belong to the Ras superfamily of small GTP binding proteins. Rap1B is known to antagonize the mitotic and transforming activity of Ras. Rap1B can be activated by cAMP known to either stimulate or inhibit cell proliferation. The deletion of 17 C-terminal amino acids in Rap1B äC leads to the loss of the phosphorylation site Ser179 and the geranyl-geranylation site. Protein preparation is 53% GDP- and 47% GTP-loaded, measured by HPLC.
Formulation	Liquid in 64 mM Tris- HCl, pH 7.0 + 5 mM DTE + 400 mM NaCl + 10 mM MgCl2 + 0.1 mM GDP.
Molecular Weight	19.0 kDa (167 amino acids)
Storage and Stability	Store at -80C. Product is stable for 12 months when stored as directed. Avoid repeated freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 3/28/2025

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