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Recombinant Human GTPase HRas G12V Mutant

Recombinant Human GTPase HRas G12V Mutant

Item no.	CS-CSI11663
Manufacturer	Cell Sciences
Amount	50 ug
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Adenocarcinoma Cytoskeleton By Organ Lung Cancer Colorectal Cancer small GTPases Ras Subfamily
Type	Proteins
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	95% by SDS-PAGE
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	HRAS1, K-RAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, N-RAS, RASH1
Available
Description	Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. HRas is one of the classic human Ras proteins (H-, N-, KRas4A, and K-Ras4B). The mutation G12V leads to elimination of the intrinsic GTPase activity. H-Ras (G12V) is effective in activation of PI3K and PKB, whereas N-Ras and K-Ras are more potent towards MAP kinase.
Formulation	Liquid. Supplied in 64 mM Tris-HCl, pH 7.2 + 10 mM MgCl2 and 5 mM DTE.
Storage and Stability	Quality guaranteed for 12 months Store at -80C Avoid freeze / thaw cycles

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 3/28/2025

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