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Recombinant Human GTPase HRas S17N

Recombinant Human GTPase HRas S17N

Item no.	CS-CSI11661
Manufacturer	Cell Sciences
Amount	50 ug
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Apoptosis Adenocarcinoma Cytoskeleton Mesothelioma Senescence By Organ Lung Cancer Bladder Cancer Colorectal Cancer small GTPases Ras Subfamily
Type	Proteins
Specific against	Human (Homo sapiens)
Purity	> 95% by SDS-PAGE
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	HRAS1, GTPase HRas, K-RAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, N-RAS, RASH1, GTP- and GDP-binding peptide B, Ha-Ras1 proto-oncoprotein, OTTHUMP00000162769, OTTHUMP00000166053, OTTHUMP00000166055, Ras family small GTP binding protein H-Ras, c-has/bas p21 protein, c-ras-Ki-2 activated oncogene, p19 H-RasIDX protein, transformation gene: oncogene HAMSV, transforming protein p21
Available
Description	Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. HRas is one of the classic human Ras proteins (H-, N-, KRas4A, and K-Ras4B). H-RasdeltaC (aa 1-171) lacks the C-terminus with the CaaX recognition sequence necessary for anchoring Ras into the plasma membrane. The mutation S17N results in a 40-fold increase in the affinity for GTP without affecting its affinity for GDP. Protein preparation is 95% GDP- and 5% GTP-loaded, measured by HPLC.
Formulation	Liquid. Supplied in 64 mM Tris-HCl, pH 7.2 + 10 mM MgCl2 and 5 mM DTE.
Molecular Weight	19.5 kDa (171 amino acids)
Storage and Stability	Quality guaranteed for 12 months Store at -80C Avoid freeze / thaw cycles

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 3/28/2025

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