Recombinant Human KGF-2/FGF-10

Fibroblast growth factor 10 belongs to the fibroblast growth factor (FGF) family which is involved in a variety of biological processes such as embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Like most other FGF family members, FGF-10 also has a heparin-binding domain and it plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. In addition, FGF-10 may play a role in wound healing and is required for normal branching morphogenesis. Recombinant human FGF-10 contains 208 amino acids and it shares 92% and 95% amino acid sequence identity with mouse and rat FGF-10. Defects in FGF-10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands and lacrimo-auriculo-dento-digitial syndrome. Recombinant Human FGF-10 is composed of 169 amino acid residues (aa 40-208).

Lyophilized from a 0.2 um filtered, concentrated (1mg/ml) solution in PBS, pH 7.4.

Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions.

>1.0 x 104 IU/mg