Comparison

Recombinant Human IL-2 HQ

Item no. CS-CRI254A
Manufacturer Cell Sciences
Amount 10 ug
Category
Type Proteins
Specific against Human
Purity >95% by SDS-PAGE
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products T cell growth factor, aldesleukin, interleukin-2, involved in regulation of T-cell clonal expansion
Available
Biological Activity
Bioactivity is assayed by measuring the dose dependent effect of human IL-2 on proliferation of CTLL-2 cells. The EC50 for a typical batch of recombinant human IL-2 is 1.08 ng/ml.
Description
Interleukin 2 (IL-2) is a potent immunoregulatory growth factor produced by T-cells following stimulation by mitogens or allogens. IL-2 promotes growth and differentiation of various cells of the immune system, such as activated T-cells and B-cells, NK cells, lymphokine activated killer cells, monocytes and macrophages. It is essential for proper immune response, it may also be an important factor in the natural suppression of autoimmunity. IL-2 may be of use as an anti-tumor agent in cancer therapy. Human and mouse IL-2 share 56% aa sequence identity and exhibit cross-species activity. The Recombinant Human IL-2 HQ contains 133 amino acids and a 16 a.a. histidine based tag for a total lenght of 149 a.a.
Endotoxin Level
<0.005 ng per ug of product (0.05 EU/ug) as measured by turbidimetric kinetic assay.
Formulation
Lyophilized from a 0.2 um sterile filtered solution of PBS, pH 7.2.
Molecular Weight
Predicted MW = 17.5 kDa. The recombinant protein migrates with an apparent MW = 22 kDa in SDS-PAGE.
Reconstitution
Centrifuge vial prior to opening. It is recommended to reconstitute the lyophilized protein in sterile water to a concentration of no less than 100 ug/ml. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). The optimal concentration should be determined by the user for each specific application.
Storage and Stability
The lyophilized protein, though stable at room temperature for few weeks, is best stored at -20C to -80C. Reconstituted protein should be used immediately or stored in working aliquots at -20C to -80C. Avoid repeated freeze-thaw cycles.
Specificity
>1 x 10E6 U/mg

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
available

Delivery expected until 8/30/2024 

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