Item no. |
CS-CRB103B |
Manufacturer |
Cell Sciences
|
Amount |
50 ug |
Category |
|
Type |
Proteins |
Specific against |
Human |
Host |
E.coli |
Purity |
>95% as determined by SDS-PAGE analysis. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
BMP13, CDMP2, KFS, KFSL, MGC158100, MGC158101, SGM1 |
Available |
|
Biological Activity |
Determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is in the range of 2-3 ug/ml. |
Description |
BMPs (bone morphogenetic proteins) belong to the TGF-b superfamily of structurally related signaling proteins. These ligands mediate numerous physiological processes. BMPs initiate, promote and maintain cartilage and bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Expression of BMP-13 has been found in the hypertrophic chondrocytes of ossifying long bone centers. Recombinant human BMP-13/CDMP-2 is a 27 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids polypeptide chains. |
Endotoxin Level |
<0.1 ng per ug of BMP-13. |
Formulation |
Lyophilized without additives. |
Molecular Weight |
27.0 kDa |
Reconstitution |
Centrifuge vial prior to opening. The human BMP-13 should be reconstituted in water containing BSA (50 ug BSA per 1 ug protein) to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions and stored for 1 week at 2-4C or at -20C for future use. Note: Due to solubility reasons, the protein should be kept at a low pH. |
Storage and Stability |
The lyophilized protein is best stored desiccated below 0C. Reconstituted protein should be stored in working aliquots at -20C. Avoid repeated freeze-thaw cycles. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.