Item no. |
CS-CRA007B |
Manufacturer |
Cell Sciences
|
Amount |
50 ug |
Category |
|
Type |
Proteins |
Specific against |
Human (Homo sapiens) |
Host |
E.coli |
Purity |
> 95% as determined by SDS-PAGE and RP-HPLC analyses |
Sequence |
VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC DIPRCTTPPP SSGPTYQCLKGTGENYRGNV AVTVSGHTCQ HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGK |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
DKFZp779M0222, OTTHUMP00000017544 |
Available |
|
Biological Activity |
Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells, in vitro, and anti-angiogenesis, in vivo, is 5.5 x 10E5 IU/mg. |
Description |
Angiostatin K1-3 is a ca.30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth, in vitro, and, in vivo . |
Endotoxin Level |
Less than 1EU/ug of rHuAngiostatin K1-3 as determined by LAL method. |
Formulation |
Lyophilized from a 0.2 um filtered concentrated solution in 20 mM NaAc, pH5.5 + 4% mannitol. |
Molecular Weight |
30.0 kDa |
Reconstitution |
Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions. |
Storage and Stability |
This lyophilized preparation is stable at 2-4C, but should be kept desiccated at -20C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.