Rabbit Anti-Rat RANTES pAb

This polyclonal antibody, which reacts with both mouse and rat RANTES, was generated using, E. coli, -expressed amino acid 1-80 of mature rat RANTES as an immunogen. RANTES (regulated upon activation, normal T-cell expressed and secreted) is a 70-amino acid CC chemokine originally cloned from T cell-specific sequences-enriched cDNA libraries. Both human and mouse RANTES are chemotactic for monocytes. Human RANTES is also a chemoattractant for T cells and eosinophils, as well as an activator of basophils for histamine release. In contrast to other CC chemokines, RANTES is only slowly expressed after activation of leukocytes. It is involved in a number of pathological conditions like chronic inflammation and autoimmune diseases.

RANTES

4C for short term storage or -20C in small aliquots for long term storage. Avoid repeated freeze and thaw cycles.