Comparison

Rabbit Anti-Human IL-22RA1 (CT) pAb

Item no. CS-PX221A
Manufacturer Cell Sciences
Amount 100 ug
Category
Type Antibody Polyclonal
Specific against Human (Homo sapiens)
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products IL22R, CRF2-9, IL22R1, cytokine receptor family 2 member 9, IL-22 receptor subunit alpha-1, IL-22R-alpha-1, interleukin-22 receptor subunit alpha-1, IL-22RA1, zcytoR11, cytokine receptor class-II member 9
Available
Manufacturer - Category
Antibodies
Description
A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified (1-3). The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family (3, 4). IL-22R forms a complex with IL-10 receptor b chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-a 2 (IL-22RA2), was identified very recently (5-7). IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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