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Human CCL4 Protein, His Tag

Human CCL4 Protein, His Tag

Item no.	CC4-H51H3-100ug
Manufacturer	ACROBiosystems
Amount	100 ug
Quantity options	100 ug 1 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Powder
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS, Unconjugated
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping condition	Room temperature
Available
Manufacturer - Category	Under_Development / Cytokines&Growth Factors
Manufacturer - Conjugate / Tag	C-10×His, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	9.7 kDa
Description	Human CCL4 Protein, His Tag (CC4-H51H3) is expressed from E. coli cells. It contains AA Ala 24 - Asn 92 (Accession # P13236-1).
Background	CCL4, also know as MIP-1-beta, is monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B
Molecule	CCL4
Exp Region	Ala 24 - Asn 92
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 9.7 kDa.
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CC4-H51H3-100ug-safety-datasheet.pdf