Item no. |
BOS-PROTQ9BXJ7 |
Manufacturer |
Boster
|
Amount |
5ug |
Category |
|
Type |
Proteins Recombinant |
Format |
Solution |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Protein amnionless;AMN;UNQ513/PRO1028; |
Available |
|
Contents |
AMN protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM DTT. |
Description |
AMN Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 361 amino acids (20-357 a.a) and having a molecular mass of 38.2kDa. AMN is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Gene name |
AMN |
Protein function |
Necessary for efficient absorption of vitamin B12 (PubMed:12590260, PubMed:14576052). Required for normal CUBN- mediated protein transport in the kidney. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity). |
Purification |
Greater than 90.0% as determined by SDS-PAGE. |
Shipping |
Shipped with wet ice |
Short description |
AMN Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 3638.2kDa. AMN is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Storage |
Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles. |
Subcellular localization |
Apical cell membrane |
Tissue specificity |
Long isoforms are highly expressed in small intestine, colon and kidney (renal proximal tubule epithelial cells). Shorter isoforms are detected at lower levels in testis, thymus and peripheral blood leukocytes. |
Format Information |
Sterile Filtered colorless solution. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.