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Rat Endothelin 1/EDN1 ELISA Kit PicoKine®

Rat Endothelin 1/EDN1 ELISA Kit PicoKine®

Manufacturer	Boster
Category	ELISA Cardiovascular Research Hypertension ELISA & Immunoassays ELISA Kits Immunoassay
Type	Elisa-Kit
Specific against	Rat
Applications	ELISA
Amount	96 wells/kit, with removable strips.
Item no.	BOS-EK0952
Targets	EDN1
eClass 6.1	32160605
eClass 9.0	32160605
Available
Alias	Endothelin-1;ET-1;Preproendothelin-1;PPET1;Edn1;
Manufacturers Product Category	PicoKine® ELISA Kits
Manufacturers Research Category	Cancer, Cancer Metabolism, Cardiovascular, Growth Factors/Hormones, Metabolism, Metabolism Processes, Pathways and Processes, Response To Hypoxia, Signal Transduction, Vasculature
Short Description	Rat Endothelin 1/EDN1 ELISA Kit PicoKine® (96 Tests). Quantitate Rat Edn1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 0.5pg/ml.
Description	Rat Endothelin 1/EDN1 ELISA Kit PicoKine® (96 Tests). Quantitate Rat Edn1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 0.5pg/ml.
Background	The endothelins is a family of structurally and pharmacologically distinct peptides, which has been identified and sequenced in humans. Three isoforms of human endothelin have been identified: endothelin-1, -2, and -3. Endothelin-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, general circulation and brain. Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (hypertension) and heart disease.
Gene Name	EDN1
Predicted Reactivity	Bovine
Immunogen	A peptide reflecting the target protein in human. Sequence: C53-W73
Cross-reactivity	There is no detectable cross-reactivity with other relevant proteins.
Sample Type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Capture antibody\|Detection antibody	monoclonal antibody from rat\|monoclonal antibody from mouse
Storage	Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Anticoagulant	heparin or EDTA
Gene Full Name	Endothelin-1
Molecular Weight	23135 MW
Protein Function	Endothelins are endothelium-derived vasoconstrictor peptides.
Subcellular Localization	Secreted.
Protein Name	Endothelin-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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