Item no. |
BOS-EKC1723 |
Manufacturer |
Boster
|
Amount |
1 kit, containing one 96-well plate and all necessary reagents |
Category |
|
Type |
Elisa-Kit |
Applications |
ELISA |
Specific against |
Human, Mouse |
Sensitivity |
>5000 cells |
ECLASS 10.1 |
32160605 |
ECLASS 11.0 |
32160605 |
UNSPSC |
41116126 |
Alias |
Chromobox protein homolog 5;Antigen p25;Heterochromatin protein 1 homolog alpha;HP1 alpha;CBX5;HP1A; |
Available |
|
Manufacturers Product Category |
Cell-Based ELISA Kits |
Short Description |
The CBX5 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CBX5 protein expression profile in cells. The kit can be used for measuring the relative amounts of CBX5 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CBX5. |
Description |
The CBX5 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CBX5 protein expression profile in cells. The kit can be used for measuring the relative amounts of CBX5 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CBX5. |
Gene Name |
CBX5 |
Storage |
Store at 4°C for up to 6 months. |
Gene Full Name |
Chromobox protein homolog 5 |
Molecular Weight |
22225 MW |
Protein Function |
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
Subcellular Localization |
Nucleus. Chromosome. Chromosome, centromere. Colocalizes with HNRNPU in the nucleus (PubMed:19617346). Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.